Genome Assembly
Whole-genome, High Resolution Maps to Complement Sequence Assembly
The increased use of next generation sequencing has led to the generation of many genome assemblies; however, they are often incomplete and not contiguous. While long-read technologies have improved assembly contiguity, they are more expensive and still lack sufficient read length to resolve complex structures. Optical mapping technologies have been used to scaffold and improve assemblies, but the inherent limitation on resolution and precision limits utility, especially in combination with short-read data. To provide the necessary long-range information while maintaining sufficient resolution to complement next generation sequencing technologies, Nabsys has developed its HD-Mapping™ platform to construct electronic whole genome maps. By analyzing reads that are hundreds of kilobases in length, electronic detection preserves long-range information while simultaneously achieving better than 300 bp single molecule resolution.
While long-read technologies have improved genome assembly contiguity, they are more expensive and still lack the sufficient read length to resolve complex structures. To provide the necessary long-range information while maintaining sufficient resolution to complement next generation sequencing technologies, Nabsys has developed the HD-Mapping platform to construct electronic whole genome maps.
By analyzing reads that are hundreds of kilobases in length, electronic detection preserves long-range information while simultaneously achieving better than 300 bp single molecule resolution. These maps allow for accurate and complete sequence assembly scaffolding and correction.

de novo Map Assembly
Generate high-density map assemblies to characterize genome architecture and variation.

Assembly Scaffolding and Error Correction
Accurately orient and gap fragmented short or long-read sequence assemblies and correct assembly errors.