Despite being the smallest state on the US map, Rhode Island is where the American Industrial Revolution was born. From spinning textiles in the first water-powered textile mill to electrophoretically translocating high-molecular weight DNA through nanochannels, Rhode Island is home to bespoke technological innovations, including our high-definition electronic nanodetection technology. And as far as we’re concerned, this is just the beginning.
Unveiling the Power of Positional Sequencing
Nabsys harnessed the potential of solid-state nanodetectors, ushering in an era where single DNA molecules are meticulously analyzed to reveal both their location and identity over vast stretches, introducing a new technology to view genomes as whole using long-range genomic data. Our cutting-edge platform was meticulously designed using electronic nanodetection, as opposed to protein-based nanopores, to establish new benchmarks for accuracy, speed, and scalability. It promises unparalleled advantages for genome structural variation analysis, whole genome mapping, and more.
Our unwavering dedication lies in catalyzing advancements in life sciences and healthcare through the deployment of our pioneering positional sequencing platform. Nabsys was honored to be the recipient of the prestigious “$1,000 Genome” award from the National Human Genome Research Institute, a testament to our electronic approach to DNA sequencing.
A Journey of Innovation, Discovery, and Evolution
Our journey commenced with research and development rooted in Brown University, catalyzed by a grant from the Division of Materials Research at the National Science Foundation. During the height of the early 2000s, when DNA sequencing began to scale and democratize, we began to learn and understand the importance of genome mapping to complement next-generation sequencing data and aid in genome assembly, metagenomics, and more. As time went on and researchers began to truly understand the genetic basis of human disease, the growing need to identify long-range structural variants became crucial. We learned that nanodetection technology was not only better suited for genome mapping due to its ability to accurately measure the distance between DNA locations with high sensitivity, but we discovered that nanodetection outperformed current industry standards for mapping in costs, precision, and scalability. This support enabled the development of the first electronic nanodetection table-top instrument pivotal for genome mapping. Our pursuit of excellence in sequencing technology had begun, laying the foundation for an exciting future.